Sometimes, more really is more.

Progesterone quick facts

High levels of circulating progesterone:

High levels of circulating progesterone during follicular development increase fertility

PRID Delta’s surface area is 155cm2 compared with 120cm2 for a T‑shape device.

PRID Delta Progesterone releasing intra-vaginal device:

Controlled release of progesterone

The surface area of PRID Delta and its position within the animal ensures maximal contact and exchange with the vaginal environment. Increased contact surface area between the device and the vaginal mucosa increases the progesterone absorption and thus, the circulating progesterone levels.

Figure 1. Progesterone release over time by product *P0.05

Designed for Optimal cow comfort

PRID Delta’s triangular shape allows even pressure distribution on the reproductive tract, with the sides completely leaning against the vagina’s inner wall, for both maximal surface contact and animal comfort.

T-shaped devices sit straight in the vagina, applying pressure with each of their branch extremities.

Figure 2. Progesterone device positioning in the vagina

Optimal retention rate

PRID Delta has been designed to provide optimal retention rates under field conditions, as shown in Figure 3.

Figure 3. Retention rates from two separate field trials

Well tolerated by animals

PRID DELTA minimizes local reactions in the vagina with a low level of vaginal secretions and no impact on fertility!

All intravaginal devices are foreign bodies and as such, can induce a local reaction. Studies have shown that when using intravaginal devices it is normal to see increased vaginal secretions and that these disappear within three days after removal and do not affect fertility..

Vaginal secretions have no impact on fertility
Score at removal of the PRID Delta 0
(clear or no debris)
1
(small flecks of purulent debris)
> 1
(abundant flecks of purulent debris)
Vaginal Discharge 11%
(92/820)
54%
(443/820)
35%
(285/820)
Pregnancy per AI, D 32 37.9% 1 39.3% 1 42.7% 1

1 P: 0.6 Non statisticlaly significant

Figure 4. Pregnancy rates are similar between groups of cows whether or not they show vaginal discharge .

Unequalled efficacy

Cumulative 9% more cows pregnant after 1st & 2nd AI with PRID Delta

Figure 5. Final percentage of pregnant cows after 1st AI (treated with PRID Delta or T-Shape device) and 2nd AI (bred after natural estrus ~ 21 days after 1st AI) in lactating Holstein cows

PRID Delta use in breeding protocol - optimization of reproductive success

Several different breeding protocols exist for cattle. PRID Delta can be used with most of them. Contact your Ceva representative to discuss how PRID Delta can help you optimize cattle fertility.

Figure 6. Standard breeding protocol

Comparison of two intravaginal progesterone releasing devices (PRID Delta vs CIDR) in dairy cows: Blood progesterone profile and field fertility

View the study at ScienceDirect.com

Comparison of two intravaginal progesterone-releasing devices in shortened-timed artificial insemination protocols in beef cattle

View the study at ScienceDirect.com

Improve cattle fertility and increase profit with PRID Delta

The causes of poor fertility performance are many and differ from farm to farm therefore specific targeted programs need to be implemented for those specific circumstances. Do not hesitate to contact a Ceva representative to discuss how Prid Delta can help your customers improve fertility performance.

PRID Delta improves the fertility performance of your cows and therefore increases the net return of your herd by:

  • Increasing pregnancy rates
  • Shortening average days open
  • Getting your animals pregnant at the right time

PRID Delta helps to obtain better fertility, and better fertility means:

  • More milk
  • More calves
  • Efficient cow management

Directions for use

Download Now

On Farm Demonstration Video

How to PREPARE, APPLY and REMOVE the PRID DELTA device. Best practice and mistakes to avoid

For more information, do not hesitate to contact us:

Western Canada

Ruminant Regional Sales Manager:
Michelle Hutchison michelle.hutchison@ceva.com
(306) 921-6137

Ruminant Veterinary Services Manager:
Dr David Lamb
david.lamb@ceva.com

Eastern Canada

Ruminant Regional Sales Manager:
Isabelle Tremblay-Summers isabelle.tremblay-summers@ceva.com
(613) 266-1847

Ruminant Veterinary Services Manager:
Dr Anne Lemay
anne.lemay@ceva.com,

For complete product information please refer to the product label

View Compendium
Product Ceva Code AVP CDMV VP WDDC
PRID Delta 10 x 1ds C61411D Special Order 123221 3911790 136071

Bisinotto, R.S., et al. “Follicular Wave of the Ovulatory Follicle and Not Cyclic Status Influences Fertility of Dairy Cows.” Journal of Dairy Science, vol. 93, no. 8, 2010, pp. 3578–3587., doi:10.3168/jds.2010-3047. Hayashi, K., Matsui, M., Shimizu, T., Sudo, N., Sato, A., Shirasuna, K., Tetsuka, M., Kida, K., Schams, D., & Miyamoto, A. (2008). The absence of corpus luteum formation alters the endocrine profile and affects follicular development during the first follicular wave in cattle. Reproduction, 136 6, 787-97 . Wiltbank, M. C., Souza, A. H., Carvalho, P. D., Cunha, A. P., Giordano, J. O., Fricke, P. M., Baez, G. M., & Diskin, M. G. (2014). Physiological and practical effects of progesterone on reproduction in dairy cattle. Animal, 8, 70–81. https://doi.org/10.1017/s1751731114000585 Garrett, J. E., Geisert, R. D., Zavy, M. T., & Morgan, G. L. (1988). Evidence for maternal regulation of early conceptus growth and development in beef cattle, Reproduction, 84(2), 437-446. Rathbone MJ, Bunt CR, Ogle CR, Burggraaf S, Macmillan KL, Burke CR, Pickering KL (2002). Reengineering of a commercially available bovine intravaginal insert (CIDR insert) containing progesterone. J Control Release. Dec 13;85(1-3):105-15. Van Werven T, Waldeck F, Souza AH, Floch S, Englebienne M (2013). Comparison of two intravaginal progesterone releasing devices (PRID Delta vs CIDR) in dairy cows: blood progesterone profile and field fertility. Anim Reprod Sci. May;138(3-4):143-9. Walsh RB, LeBlanc SJ, Vernooy E, Leslie KE (2008). Safety of a progesterone-releasing intravaginal device as assessed from vaginal mucosal integrity and indicators of systemic inflammation in postpartum dairy cows. Can J Vet Res. Jan;72(1):43-9. Drake, E., Holden, S. A., Aublet, V., Doyle, R. C., Millar, C., Moore, S. G., Maicas, C., Randi, F., Cromie, A. R., Lonergan, P., & Butler, S. T. (2020). Evaluation of delayed timing of artificial insemination with sex-sorted sperm on pregnancy per artificial insemination in seasonal-calving, pasture-based lactating dairy cows. Journal of Dairy Science, 103(12), 12059–12068. https://doi.org/10.3168/jds.2020-18847 Santos VG, Carvalho PD, Maia C, Carneiro B, Valenza A, Crump PM, Fricke PM (2016) Adding a second prostaglandin F2α treatment to but not reducing the duration of a PRID-Synch protocol increases fertility after resynchronization of ovulation in lactating Holstein cows. J. Dairy Sci. 99:1–11

Bisinotto, R.S., et al. “Follicular Wave of the Ovulatory Follicle and Not Cyclic Status Influences Fertility of Dairy Cows.” Journal of Dairy Science, vol. 93, no. 8, 2010, pp. 3578–3587., doi:10.3168/jds.2010-3047.

Hayashi, K., Matsui, M., Shimizu, T., Sudo, N., Sato, A., Shirasuna, K., Tetsuka, M., Kida, K., Schams, D., & Miyamoto, A. (2008). The absence of corpus luteum formation alters the endocrine profile and affects follicular development during the first follicular wave in cattle. Reproduction, 136 6, 787-97.

Wiltbank, M. C., Souza, A. H., Carvalho, P. D., Cunha, A. P., Giordano, J. O., Fricke, P. M., Baez, G. M., & Diskin, M. G. (2014). Physiological and practical effects of progesterone on reproduction in dairy cattle. Animal, 8, 70–81. https://doi.org/10.1017/s1751731114000585.

Garrett, J. E., Geisert, R. D., Zavy, M. T., & Morgan, G. L. (1988). Evidence for maternal regulation of early conceptus growth and development in beef cattle, Reproduction, 84(2), 437-446.

Rathbone MJ, Bunt CR, Ogle CR, Burggraaf S, Macmillan KL, Burke CR, Pickering KL (2002). Reengineering of a commercially available bovine intravaginal insert (CIDR insert) containing progesterone. J Control Release. Dec 13;85(1-3):105-15.

Van Werven T, Waldeck F, Souza AH, Floch S, Englebienne M (2013). Comparison of two intravaginal progesterone releasing devices (PRID Delta vs CIDR) in dairy cows: blood progesterone profile and field fertility. Anim Reprod Sci. May;138(3-4):143-9.

Walsh RB, LeBlanc SJ, Vernooy E, Leslie KE (2008). Safety of a progesterone-releasing intravaginal device as assessed from vaginal mucosal integrity and indicators of systemic inflammation in postpartum dairy cows. Can J Vet Res. Jan;72(1):43-9.

Drake, E., Holden, S. A., Aublet, V., Doyle, R. C., Millar, C., Moore, S. G., Maicas, C., Randi, F., Cromie, A. R., Lonergan, P., & Butler, S. T. (2020). Evaluation of delayed timing of artificial insemination with sex-sorted sperm on pregnancy per artificial insemination in seasonal-calving, pasture-based lactating dairy cows. Journal of Dairy Science, 103(12), 12059–12068. https://doi.org/10.3168/jds.2020-18847

Santos VG, Carvalho PD, Maia C, Carneiro B, Valenza A, Crump PM, Fricke PM (2016) Adding a second prostaglandin F2α treatment to but not reducing the duration of a PRID-Synch protocol increases fertility after resynchronization of ovulation in lactating Holstein cows. J. Dairy Sci. 99:1–11